BIOPEP-UWM: Report

ID 9700
Name ACE inhibitor
sequence
ADVFNPR
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
7
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 817.8868 Monoisotopic mass 817.4070
IC50 :
485.70 µM


Bibliographic data:
Authors
Zheng Y., Li Y., Zhang Y., Ruan X., Zhang R.
Title
Purification, characterization, synthesis, in vitro ACE inhibition and in vivo antihypertensive activity of bioactive peptides derived from oil palm kernel glutelin-2 hydrolysates. J. Funct. Foods, 28, 48-58, 2017
Year Source
2017 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O


InChI=1S/C36H55N11O11/c1-18(2)28(46-31(53)23(17-27(49)50)43-29(51)19(3)37)33(55)44-22(15-20-9-5-4-6-10-20)30(52)45-24(16-26(38)48)34(56)47-14-8-12-25(47)32(54)42-21(35(57)58)11-7-13-41-36(39)40/h4-6,9-10,18-19,21-25,28H,7-8,11-17,37H2,1-3H3,(H2,38,48)(H,42,54)(H,43,51)(H,44,55)(H,45,52)(H,46,53)(H,49,50)(H,57,58)(H4,39,40,41)/t19-,21-,22-,23-,24-,25-,28-/m0/s1


InChIKey: KDGPICQIDWPGDU-IVXOHGEOSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Hypotensive peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9711)
Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9712)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9711; 9712