BIOPEP-UWM: Report

ID 9703
Name Inhibitor of alpha-amylase
sequence
LPLLR
Function:
Inhibitor of alpha-amylase (EC 3.2.1.1)
 
Number of residues
5
Activity code
aami
Activity :
alpha-amylase inhibitor
Chemical mass 610.7869 Monoisotopic mass 610.4154
IC50 :
2000.00 µM


Bibliographic data:
Authors
Wang J., Wu T., Fang L., Liu C., Liu X., Li H., Shi J., Li M., Min W.
Title
Anti-diabetic effect by walnut (Juglans mandshurica Maxim.)-derived peptide LPLLR through inhibiting α-glucosidase and α-amylase, and alleviating insulin resistance of hepatic HepG2 cells. J. Funct. Foods, 69, 103944, 2020
Year Source
2020 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C29H54N8O6/c1-16(2)13-19(30)27(41)37-12-8-10-23(37)26(40)36-22(15-18(5)6)25(39)35-21(14-17(3)4)24(38)34-20(28(42)43)9-7-11-33-29(31)32/h16-23H,7-15,30H2,1-6H3,(H,34,38)(H,35,39)(H,36,40)(H,42,43)(H4,31,32,33)/t19-,20-,21-,22-,23-/m0/s1

InChIKey= OAJZRPXPLBASHH-VUBDRERZSA-N


Antidiabetic peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9692)
Inhibitor of alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides (ID 9705)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9692; 9705