BIOPEP-UWM: Report

ID 9709
Name ACE inhibitor
sequence
VIEPR

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
5
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 612.7169 Monoisotopic mass 612.3584
IC50 :
632.00 µM



Bibliographic data:
Authors
Zheng Y., Li Y., Zhang Y., Ruan X., Zhang R.
Title
Purification, characterization, synthesis, in vitro ACE inhibition andin vivo antihypertensive activity of bioactive peptides derived from oilpalm kernel glutelin-2 hydrolysates. J. Funct. Foods, 28, 48-58, 2017
Year Source
2017 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O


InChI=1S/C27H48N8O8/c1-5-15(4)21(34-23(39)20(28)14(2)3)24(40)32-16(10-11-19(36)37)25(41)35-13-7-9-18(35)22(38)33-17(26(42)43)8-6-12-31-27(29)30/h14-18,20-21H,5-13,28H2,1-4H3,(H,32,40)(H,33,38)(H,34,39)(H,36,37)(H,42,43)(H4,29,30,31)/t15-,16-,17-,18-,20-,21-/m0/s1


InChIKey: ICMMMJUYZHKULL-ZKHIMWLXSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Hypotensive peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9717)
Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9718)



Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9717; 9718