BIOPEP-UWM: Report

ID 9711
Name Hypotensive peptide
sequence
ADVFNPR

Function:
Lowering blood pressure in rats
 
Number of residues
7
Activity code
hyp
Activity :
hypotensive
Chemical mass 817.8868 Monoisotopic mass 817.4070
EC50 :
0.00 µM



Bibliographic data:
Authors
Zheng Y., Li Y., Zhang Y., Ruan X., Zhang R.
Title
Purification, characterization, synthesis, in vitro ACE inhibition and in vivo antihypertensive activity of bioactive peptides derived from oil palm kernel glutelin-2 hydrolysates. J. Funct. Foods, 28, 48-58, 2017
Year Source
2017 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O


InChI=1S/C36H55N11O11/c1-18(2)28(46-31(53)23(17-27(49)50)43-29(51)19(3)37)33(55)44-22(15-20-9-5-4-6-10-20)30(52)45-24(16-26(38)48)34(56)47-14-8-12-25(47)32(54)42-21(35(57)58)11-7-13-41-36(39)40/h4-6,9-10,18-19,21-25,28H,7-8,11-17,37H2,1-3H3,(H2,38,48)(H,42,54)(H,43,51)(H,44,55)(H,45,52)(H,46,53)(H,49,50)(H,57,58)(H4,39,40,41)/t19-,21-,22-,23-,24-,25-,28-/m0/s1


InChIKey: KDGPICQIDWPGDU-IVXOHGEOSA-N

Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 9700)
Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9712)



Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9700; 9712