BIOPEP-UWM: Report

ID 9720
Name ACE inhibitor
sequence
ASQSIWLPGWL

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
11
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 1257.4327 Monoisotopic mass 1256.6533
IC50 :
4.02 µM



Bibliographic data:
Authors
Montone, C. M., Zenezini Chiozzi, R., Marchetti, N., Cerrato, A., Antonelli, M., Capriotti, A. L., Cavaliere C., Piovesana S.,Laganà A.
Title
Peptidomic Approach for the Identification of Peptides with Potential Antioxidant and Anti-Hyperthensive Effects Derived From Asparagus By-Products. Molecules, 24(19), 3627, 2019
Year Source
2019 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@H](CC)C)C(=O)N[C@@H](CC1=C[N]([H])C2=CC=CC=C12)C(=O)N[C@@H](CC(C)C)C(=O)N3[C@@H](CCC3)C(=O)NCC(=O)N[C@@H](CC4=C[N]([H])C5=CC=CC=C45)C(=O)N[C@@H](CC(C)C)C(=O)O

InChI=1S/C61H88N14O15/c1-8-33(6)51(74-57(85)47(30-77)73-53(81)41(19-20-49(63)78)68-56(84)46(29-76)72-52(80)34(7)62)59(87)69-43(25-36-27-65-40-17-12-10-15-38(36)40)55(83)70-44(22-31(2)3)60(88)75-21-13-18-48(75)58(86)66-28-50(79)67-42(54(82)71-45(61(89)90)23-32(4)5)24-35-26-64-39-16-11-9-14-37(35)39/h9-12,14-17,26-27,31-34,41-48,51,64-65,76-77H,8,13,18-25,28-30,62H2,1-7H3,(H2,63,78)(H,66,86)(H,67,79)(H,68,84)(H,69,87)(H,70,83)(H,71,82)(H,72,80)(H,73,81)(H,74,85)(H,89,90)/t33-,34-,41-,42-,43-,44-,45-,46-,47-,48-,51-/m0/s1


InChIKey: CMCBXEULYRPOSV-ZTIGKAIHSA-N



Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001




Database reference: