BIOPEP-UWM: Report

ID 9729
Name ACE inhibitor
sequence
VVR
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 372.4618 Monoisotopic mass 372.2478
IC50 :
249.70 µM


Bibliographic data:
Authors
Manoharan S., Shuib A. S., Abdullah N., Bin Mohamad S., Aminudin N.
Title
Characterisation of novel angiotensin-I-converting enzyme inhibitory tripeptide, Gly-Val-Arg derived from mycelium of Pleurotus pulmonarius. Process Biochem., 62, 215–222, 2017
Year Source
2017 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C16H32N6O4/c1-8(2)11(17)13(23)22-12(9(3)4)14(24)21-10(15(25)26)6-5-7-20-16(18)19/h8-12H,5-7,17H2,1-4H3,(H,21,24)(H,22,23)(H,25,26)(H4,18,19,20)/t10-,11-,12-/m0/s1

InChIKey=RTJPAGFXOWEBAI-SRVKXCTJSA-N


Predicted ligand of furin (EC 3.4.21.75) (MEROPS ID: S08.071; PDB ID: 6HLD) according to the BIOPEP-UWM Virtual database (ID 273)


Database reference:
PubChem: CID 25123284