BIOPEP-UWM: Report

ID 9748
Name PEP inhibitor
sequence
PIHNSLPQNIPPLTQTPV
Function:
Inhibitor of prolyl oligopeptidase (EC 3.4.21.26) (MEROPS ID: S09.001)
 
Number of residues
18
Activity code
am
Activity :
antiamnestic
Chemical mass 1966.2351 Monoisotopic mass 1965.0650
IC50 :
29.80 µM


Bibliographic data:
Authors
Hsieh C. H., Wang T. Y., Hung C. C., Hsieh Y. L., Hsu, K. C.
Title
Isolation of prolyl endopeptidase inhibitory peptides from a sodium caseinate hydrolysate. Food & Function, 7(1), 565-573, 2016
Year Source
2016 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N1[C@@H](CCC1)C(=O)N[C@@H]([C@H](CC)C)C(=O)N[C@@H](CC2=C[N]([H])C=N2)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N3[C@@H](CCC3)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@H](CC)C)C(=O)N4[C@@H](CCC4)C(=O)N5[C@@H](CCC5)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@H](O)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@H](O)C)C(=O)N6[C@@H](CCC6)C(=O)N[C@@H](C(C)C)C(=O)O

InChI=1S/C89H144N24O26/c1-13-45(9)68(106-72(121)50-20-15-29-95-50)83(132)102-54(36-49-39-94-41-96-49)75(124)100-55(37-65(92)119)76(125)104-58(40-114)79(128)103-57(35-43(5)6)85(134)110-30-16-21-59(110)80(129)97-51(25-27-63(90)117)73(122)99-56(38-66(93)120)78(127)107-69(46(10)14-2)87(136)113-33-19-24-62(113)86(135)111-31-17-22-60(111)81(130)101-53(34-42(3)4)77(126)108-70(47(11)115)84(133)98-52(26-28-64(91)118)74(123)109-71(48(12)116)88(137)112-32-18-23-61(112)82(131)105-67(44(7)8)89(138)139/h39,41-48,50-62,67-71,95,114-116H,13-38,40H2,1-12H3,(H2,90,117)(H2,91,118)(H2,92,119)(H2,93,120)(H,94,96)(H,97,129)(H,98,133)(H,99,122)(H,100,124)(H,101,130)(H,102,132)(H,103,128)(H,104,125)(H,105,131)(H,106,121)(H,107,127)(H,108,126)(H,109,123)(H,138,139)/t45-,46-,47+,48+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,67-,68-,69-,70-,71-/m0/s1


InChIKey: ZNCFYPHKGIYFFO-JNNBABLMSA-N


Database reference: