BIOPEP-UWM: Report

ID 9817
Name Alpha-glucosidase inhibitor
sequence
IIAPPER

Function:
Inhibitor of alpha-glucosidase (EC 3.2.1.20)
 
Number of residues
7
Activity code
glui
Activity :
alpha-glucosidase inhibitor
Chemical mass 794.9360 Monoisotopic mass 794.4636
IC50 :
28.75 µM



Bibliographic data:
Authors
Zielińska E., Karaś M., Baraniak B., Jakubczyk A.
Title
Evaluation of ACE, alpha‑glucosidase, and lipase inhibitory activities of peptides obtained by in vitro digestion of selected species of edible insects. Eur. Food Res. Technol., 246, 1361-1369, 2020
Year Source
2020 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C36H62N10O10/c1-6-19(3)27(37)31(51)44-28(20(4)7-2)32(52)41-21(5)33(53)46-18-10-13-25(46)34(54)45-17-9-12-24(45)30(50)42-22(14-15-26(47)48)29(49)43-23(35(55)56)11-8-16-40-36(38)39/h19-25,27-28H,6-18,37H2,1-5H3,(H,41,52)(H,42,50)(H,43,49)(H,44,51)(H,47,48)(H,55,56)(H4,38,39,40)/t19-,20-,21-,22-,23-,24-,25-,27-,28-/m0/s1

InChIKey=ZHQCNOJJTASHDW-ADWUDYDCSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 9815)
Inhibitor of pancreatic lipase according to the BIOPEP-UWM database of bioactive peptides (ID 9816)



Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9815; 9816