BIOPEP-UWM: Report

ID 9820
Name Alpha-glucosidase inhibitor
sequence
LAPSTIK
Function:
Inhibitor of alpha-glucosidase (EC 3.2.1.20)
 
Number of residues
7
Activity code
glui
Activity :
alpha-glucosidase inhibitor
Chemical mass 728.8747 Monoisotopic mass 728.4418
IC50 :
62.55 µM


Bibliographic data:
Authors
Zielińska E., Karaś M., Baraniak B., Jakubczyk A.
Title
Evaluation of ACE, alpha‑glucosidase, and lipase inhibitory activities of peptides obtained by in vitro digestion of selected species of edible insects. Eur. Food Res. Technol., 246, 1361-1369, 2020
Year Source
2020 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CCCCN)C(=O)O

InChI=1S/C33H60N8O10/c1-7-18(4)25(30(47)37-22(33(50)51)11-8-9-13-34)39-31(48)26(20(6)43)40-28(45)23(16-42)38-29(46)24-12-10-14-41(24)32(49)19(5)36-27(44)21(35)15-17(2)3/h17-26,42-43H,7-16,34-35H2,1-6H3,(H,36,44)(H,37,47)(H,38,46)(H,39,48)(H,40,45)(H,50,51)/t18-,19-,20+,21-,22-,23-,24-,25-,26-/m0/s1

InChIKey=RZGYKXWBKAWARZ-VOPNCDMXSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 9818)
Inhibitor of pancreatic lipase according to the BIOPEP-UWM database of bioactive peptides (ID 9819)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9818; 9819