BIOPEP-UWM: Report

ID 9823
Name ACE inhibitor
sequence
KVEGDLK

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
7
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 787.8988 Monoisotopic mass 787.4425
IC50 :
4.66 µM



Bibliographic data:
Authors
Zielińska E., Karaś M., Baraniak B., Jakubczyk A.
Title
Evaluation of ACE, alpha‑glucosidase, and lipase inhibitory activities of peptides obtained by in vitro digestion of selected species of edible insects. Eur. Food Res. Technol., 246, 1361-1369, 2020
Year Source
2020 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)NCC(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)O

InChI=1S/C34H61N9O12/c1-18(2)15-23(31(51)41-22(34(54)55)10-6-8-14-36)42-32(52)24(16-27(47)48)39-25(44)17-38-30(50)21(11-12-26(45)46)40-33(53)28(19(3)4)43-29(49)20(37)9-5-7-13-35/h18-24,28H,5-17,35-37H2,1-4H3,(H,38,50)(H,39,44)(H,40,53)(H,41,51)(H,42,52)(H,43,49)(H,45,46)(H,47,48)(H,54,55)/t20-,21-,22-,23-,24-,28-/m0/s1

InChIKey=USIFMUVFRAKZRH-BIWWIESBSA-N


Inhibitor of pancreatic lipase according to the BIOPEP-UWM database of bioactive peptides (ID 9824)
Inhibitor of alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides (ID 9825)
Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9439)



Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9439; 9824; 9825