BIOPEP-UWM: Report

ID 9827
Name Pancreatic lipase inhibitor
sequence
NYVADGLG
Function:
Pancreatic lipase inhibitor
 
Number of residues
8
Activity code
plip
Activity :
pancreatic lipase inhibitor
Chemical mass 807.8457 Monoisotopic mass 807.3750
IC50 :
143.17 µM


Bibliographic data:
Authors
Zielińska E., Karaś M., Baraniak B., Jakubczyk A.
Title
Evaluation of ACE, alpha‑glucosidase, and lipase inhibitory activities of peptides obtained by in vitro digestion of selected species of edible insects. Eur. Food Res. Technol., 246, 1361-1369, 2020
Year Source
2020 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(=O)O)C(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(=O)O

InChI=1S/C35H53N9O13/c1-16(2)10-22(32(54)39-15-28(50)51)41-26(47)14-38-33(55)24(13-27(48)49)42-30(52)18(5)40-35(57)29(17(3)4)44-34(56)23(11-19-6-8-20(45)9-7-19)43-31(53)21(36)12-25(37)46/h6-9,16-18,21-24,29,45H,10-15,36H2,1-5H3,(H2,37,46)(H,38,55)(H,39,54)(H,40,57)(H,41,47)(H,42,52)(H,43,53)(H,44,56)(H,48,49)(H,50,51)/t18-,21-,22-,23-,24-,29-/m0/s1

InChIKey=RUDICKKMQRBXRT-LXFJOMDISA-N


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9440)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 9826)
Inhibitor of Alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides (ID 9828)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9440; 9826; 9828