BIOPEP-UWM: Report

ID 9829
Name ACE inhibitor
sequence
AAAPVAVAK

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
9
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 796.9518 Monoisotopic mass 796.4792
IC50 :
10.45 µM



Bibliographic data:
Authors
Zielińska E., Karaś M., Baraniak B., Jakubczyk A.
Title
Evaluation of ACE, alpha‑glucosidase, and lipase inhibitory activities of peptides obtained by in vitro digestion of selected species of edible insects. Eur. Food Res. Technol., 246, 1361-1369, 2020
Year Source
2020 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)O

InChI=1S/C36H64N10O10/c1-17(2)26(33(52)40-21(7)30(49)43-24(36(55)56)13-10-11-15-37)44-31(50)22(8)41-34(53)27(18(3)4)45-32(51)25-14-12-16-46(25)35(54)23(9)42-29(48)20(6)39-28(47)19(5)38/h17-27H,10-16,37-38H2,1-9H3,(H,39,47)(H,40,52)(H,41,53)(H,42,48)(H,43,49)(H,44,50)(H,45,51)(H,55,56)/t19-,20-,21-,22-,23-,24-,25-,26-,27-/m0/s1

InChIKey=WUQCVEBPAYSGPV-JOXZBDCSSA-N



Pancreatic lipase inhibitor according to the BIOPEP-UWM database of bioactive peptides (ID 9830)
Inhibitor of Alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides (ID 9831)
Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9441)



Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9441; 9830; 9831