BIOPEP-UWM: Report

ID 9830
Name Pancreatic lipase inhibitor
sequence
AAAPVAVAK
Function:
Inhibitor of pancreatic lipase
 
Number of residues
9
Activity code
plip
Activity :
pancreatic lipase inhibitor
Chemical mass 796.9518 Monoisotopic mass 796.4792
IC50 :
64.35 µM


Bibliographic data:
Authors
Zielińska E., Karaś M., Baraniak B., Jakubczyk A.
Title
Evaluation of ACE, alpha‑glucosidase, and lipase inhibitory activities of peptides obtained by in vitro digestion of selected species of edible insects. Eur. Food Res. Technol., 246, 1361-1369, 2020
Year Source
2020 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)O

InChI=1S/C36H64N10O10/c1-17(2)26(33(52)40-21(7)30(49)43-24(36(55)56)13-10-11-15-37)44-31(50)22(8)41-34(53)27(18(3)4)45-32(51)25-14-12-16-46(25)35(54)23(9)42-29(48)20(6)39-28(47)19(5)38/h17-27H,10-16,37-38H2,1-9H3,(H,39,47)(H,40,52)(H,41,53)(H,42,48)(H,43,49)(H,44,50)(H,45,51)(H,55,56)/t19-,20-,21-,22-,23-,24-,25-,26-,27-/m0/s1

InChIKey=WUQCVEBPAYSGPV-JOXZBDCSSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 9829)
Inhibitor of Alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides (ID 9831)
Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9441)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9441; 9829; 9831