BIOPEP-UWM: Report

ID 9835
Name Pancreatic lipase inhibitor
sequence
AGDDAPR

Function:
Inhibitor of pancreatic lipase
 
Number of residues
7
Activity code
plip
Activity :
pancreatic lipase inhibitor
Chemical mass 700.6963 Monoisotopic mass 700.3130
IC50 :
110.61 µM



Bibliographic data:
Authors
Zielińska E., Karaś M., Baraniak B., Jakubczyk A.
Title
Evaluation of ACE, alpha‑glucosidase, and lipase inhibitory activities of peptides obtained by in vitro digestion of selected species of edible insects. Eur. Food Res. Technol., 246, 1361-1369, 2020
Year Source
2020 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C)C(=O)NCC(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C27H44N10O12/c1-12(28)21(43)32-11-18(38)34-15(9-19(39)40)23(45)36-16(10-20(41)42)22(44)33-13(2)25(47)37-8-4-6-17(37)24(46)35-14(26(48)49)5-3-7-31-27(29)30/h12-17H,3-11,28H2,1-2H3,(H,32,43)(H,33,44)(H,34,38)(H,35,46)(H,36,45)(H,39,40)(H,41,42)(H,48,49)(H4,29,30,31)/t12-,13-,14-,15-,16-,17-/m0/s1

InChIKey=DWTQGNOZCAMFKL-UYLCUJDWSA-N


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9443)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 9834)
Inhibitor of Alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides (ID 9836)



Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9443; 9834; 9836