BIOPEP-UWM: Report

ID 9841
Name Pancreatic lipase inhibitor
sequence
AIGVGAIER
Function:
Inhibitor of pancreatic lipase
 
Number of residues
9
Activity code
plip
Activity :
pancreatic lipase inhibitor
Chemical mass 885.0170 Monoisotopic mass 884.5064
IC50 :
56.47 µM


Bibliographic data:
Authors
Zielińska E., Karaś M., Baraniak B., Jakubczyk A.
Title
Evaluation of ACE, alpha‑glucosidase, and lipase inhibitory activities of peptides obtained by in vitro digestion of selected species of edible insects. Eur. Food Res. Technol., 246, 1361-1369, 2020
Year Source
2020 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)NCC(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C38H68N12O12/c1-9-19(5)29(49-31(55)21(7)39)35(59)44-17-26(52)48-28(18(3)4)34(58)43-16-25(51)45-22(8)32(56)50-30(20(6)10-2)36(60)46-23(13-14-27(53)54)33(57)47-24(37(61)62)12-11-15-42-38(40)41/h18-24,28-30H,9-17,39H2,1-8H3,(H,43,58)(H,44,59)(H,45,51)(H,46,60)(H,47,57)(H,48,52)(H,49,55)(H,50,56)(H,53,54)(H,61,62)(H4,40,41,42)/t19-,20-,21-,22-,23-,24-,28-,29-,30-/m0/s1

InChIKey=ZUMQZVQMEVLCAX-RBXVSGTMSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 9840)
Inhibitor of alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides (ID 9842)
Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9445)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9445; 9840; 9842