BIOPEP-UWM: Report

ID 9908
Name ACE inhibitor
sequence
PPL

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 325.4022 Monoisotopic mass 325.1995
IC50 :
427.15 µM



Bibliographic data:
Authors
Wang Z., Zhang S., Jin H., Wang W., Huo J., Zhou L., Wang Y., Feng F., Zhang L.
Title
Angiotensin-I-converting enzyme inhibitory peptides: Chemical feature based pharmacophore generation. Eur. J. Med. Chem., 46, 3428-3433, 2011
Year Source
2011 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)O

InChI=1S/C16H27N3O4/c1-10(2)9-12(16(22)23)18-14(20)13-6-4-8-19(13)15(21)11-5-3-7-17-11/h10-13,17H,3-9H2,1-2H3,(H,18,20)(H,22,23)/t11-,12-,13-/m0/s1

InChIKey=CGSOWZUPLOKYOR-AVGNSLFASA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8652)



Database reference:
AHTPDB: ID ahtpdb_1957

BindingDB: ID 50348859

BioPepDB: ID biopep01080

BIOPEP-UWM database of bioactive peptides: ID 8652

ChEBI: ID 162598

ChEMBL: ID CHEMBL1807691

ChemSpider: ID 10032763

EROP-Moscow: ID E26062

FeptideDB: ID 8652

J-GLOBAL: ID 201507031190847837

Nikkaji: ID J3.367.833I

PubChem: CID 11858292

SATPdb: ID satpdb10190

ZINC: ID ZINC000036489331