BIOPEP-UWM: Report

ID 9940
Name ACE inhibitor
sequence
WVYY

Function:
Inhibitor of angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
4
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 629.7012 Monoisotopic mass 629.2840
IC50 :
27.00 µM



Bibliographic data:
Authors
Girgih AT, He R, Aluko RE.
Title
Kinetics and molecular docking studies of the inhibitions of angiotensin converting enzyme and renin activities by hemp seed (Cannabis sativa L.) peptides. J. Agric. Food Chem. 62, 4135−4144, 2014
Year Source
2014 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@H](CC1=C[N]([H])C2=CC=CC=C12)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(=O)N[C@@H](CC4=CC=C(C=C4)O)C(=O)O

InChI= 1S/C34H39N5O7/c1-19(2)30(39-31(42)26(35)17-22-18-36-27-6-4-3-5-25(22)27)33(44)37-28(15-20-7-11-23(40)12-8-20)32(43)38-29(34(45)46)16-21-9-13-24(41)14-10-21/h3-14,18-19,26,28-30,36,40-41H,15-17,35H2,1-2H3,(H,37,44)(H,38,43)(H,39,42)(H,45,46)/t26-,28-,29-,30-/m0/s1

InChIKey: PRZWESBMSHMINZ-SYKYGTKKSA-N


Antioxidative peptide according to the EROP-Moscow databases




Database reference:
EROP-Moscow: ID E24210