BIOPEP-UWM: Report

ID 9941
Name ACE inhibitor
sequence
WYT
Function:
Inhibitor of angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 468.5012 Monoisotopic mass 468.2002
IC50 :
54.00 µM


Bibliographic data:
Authors
Girgih AT, He R, Aluko RE.
Title
Kinetics and molecular docking studies of the inhibitions of angiotensin converting enzyme and renin activities by hemp seed (Cannabis sativa L.) peptides. J. Agric. Food Chem. 62, 4135−4144, 2014
Year Source
2014 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@H](CC1=C[N]([H])C2=CC=CC=C12)C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(=O)N[C@@H]([C@H](O)C)C(=O)O

InChI= 1S/C24H28N4O6/c1-13(29)21(24(33)34)28-23(32)20(10-14-6-8-16(30)9-7-14)27-22(31)18(25)11-15-12-26-19-5-3-2-4-17(15)19/h2-9,12-13,18,20-21,26,29-30H,10-11,25H2,1H3,(H,27,31)(H,28,32)(H,33,34)/t13-,18+,20+,21+/m1/s1

InChIKey: YTHWAWACWGWBLE-MNSWYVGCSA-N


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10016)
Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID A01.007) 001) according to the BIOPEP-UWM database of bioactive peptides (ID 10017)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 10016; 10017

EROP-Moscow: ID E24212

PubChem: CID 71472028