BIOPEP-UWM: Report

ID 1100
Name beta-casein, gen. var. B, bovine (Bos taurus)
sequence
RELEELNVPGEIVESLSSSEESITRINKKIEKFQSEEQQQTEDELQDKIHPFAQTQSLVYPFPGPIPNSLPQNIPPLTQTPVVVPPFLQPEVMGVSKVKEAMAPKHKEMPFPKYPVEPFTERQSLTLTDVENLHLPLPLLQSWMHQPHQPLPPTVMFPPQSVLSLSQSKVLPVPQKAVPYPQRDMPIQAFLLYQEPVLGPVRGPFPIIV
Function:
Important role in determination of the surface properties of the casein micelles. Casoparan acts as a macrophage activator, increasing the phagocytic activity of macrophages and peroxide release from macrophages. It also acts as a bradykinin-potentiating peptide. Casohypotensin acts as a bradykinin-potentiating peptide. Induces hypotension in rats. Acts as a strong competitive inhibitor of endo-oligopeptidase A. Antioxidant peptide has antioxidant activity. Ref.: Swiss-|Prot database (www.expasy.org).
 
Number of residues 209
Chemical mass 23652.0371 Monoisotopic mass 23637.3490


Bibliographic data:
Authors
Grosclaude F., Mahe M.-F., Mercier J.-C., Ribadeau-Dumas B.
Title
Characterization of genetic variants of alpha-S1 and beta bovine caseins. Eur. J. Biochem. 26:328-337.
Year Source
1972 Journal


Additional information:
Protein known as: allergen Bos d 8. Chain: from 16 to 224; signal peptide: from 1 to 15. Important role in determination of the surface properties of the casein micelles. Casoparan acts as a macrophage activator, increasing the phagocytic activity of macrophages and peroxide release from macrophages. It also acts as a bradykinin-potentiating peptide. Casohypotensin acts as a bradykinin-potentiating peptide. Induces hypotension in rats. Acts as a strong competitive inhibitor of endo-oligopeptidase A. Antioxidant peptide has antioxidant activity.
Ref.: Swiss-Prot database (www.expasy org).


Database reference:
SWISS PROT entry name: CASB_BOVIN, accession number: P02666