BIOPEP-UWM: Report

ID 1252
Name Glucocorticoid receptor, rainbow trout ( Oncorhynchus mykiss)
sequence
MDPGGLKHSKDKGLAFGKLSESSVEGSFSGDTGGSKSTTSTSLMHLPGSRPQPPARDSANGLNVTTTQMELSTGGLTIEEAEVKVMEKAIRMQQPQKPQQNQQLFENFALLEASIADLNRSNTPGSSVLGRPHDLFSLKTENFSPMDKDRLDMGSVSFGQSQKDLDVNERLLGDNTMDILQDLDLPGSLSDLNEFYVSDEAAFLSSLSVEDVLLEDGNMETKPIDCSNGGNCTNVDSADQQKQLLEAGVSMPVIKTEEDADTSFIQLCTPGVIKQENDRRSFCQISSLDLPSTHNSAGSISGPSYPYGANTSTAVSLQQDQKPVFGLYPPLPSVSDSWNRGNGYATGSGMSSSSFPVGFSSPKARPEASGSASSAPAKPSGPTHKICLVCSDEASGCHYGVLTCGSCKVFFKRAVEGWRARQNTDGQHNYLCAGRNDCIIDKIRRKNCPACRFRKCLQAGMNLEARKNKKLIRLKGQQTTMEPNPPPPDERACALIPKSMPQLVPTMLSLLKAIEPEAIYSGYDSTIPDTSTRLMTTLNRLGGQQVVSAVKWAKSLPGFRNLHLDDQMTLLQCSWLFLMSFGLGWRSYQQCNGGMLCFAPDLVINDERMKLPYMTDQCEQMLKISTEFVRLQVSYDEYLCMKVLLLLSTVPKDGLKSQAVFDEIRMTYIKELGKAIVKREENSSQNWQRFYQLTKLLDSMQEMVGGLLQICFYTFVNKSLSVEFPEMLAEIISNQLPKFKDGSVKPLLFHALNHDTMP

Function:
Receptor for glucocorticoids (GC). Acts as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues.
 
Number of residues 758
Chemical mass 83343.7176 Monoisotopic mass 83290.9255



Bibliographic data:
Authors
Ducouret B., Tujague M., Ashraf J., Mouchel N., Servel N., Valotaire Y., Thompson E.B.
Title
Cloning of a teleost fish glucocorticoid receptor shows that it contains a deoxyribonucleic acid-binding domain different from that of mammals. Endocrinology 136:3774-3783(1995).
Year Source
1995 Journal



Additional information:



Database reference:
Swiss-Prot entry name: GCR_ONCMY, primary accession number: P49843