BIOPEP-UWM: Sensory peptide/amino acid data
ID
Name
Sequence
GY
Chemical Mass
Number of residues
Monoisotopic Mass
EC50
µM
Additional Information
BIOPEP database of sensory peptides and amino acids SMILES: c1cc(ccc1C[C@@H](C(=O)O)NC(=O)CN)O InChI=1S/C11H14N2O4/c12-6-10(15)13-9(11(16)17)5-7-1-3-8(14)4-2-7/h1-4,9,14H,5-6,12H2,(H,13,15)(H,16,17)/t9-/m0/s1 InChIKey: XBGGUPMXALFZOT-VIFPVBQESA-N Another references concerning bitter taste: Asao M., Iwamura H., Akamatsu M., Fujita T., 1987, Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives. J. Med. Chem., 30, 1873-1879 Collantes E. R., Dunn W. J., 1995, Amino acid side chain descriptors for quantitative structure-activity relationship studies of peptide analogues. J. Med. Chem., 38, 2705-2713 Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to BIOPEP database of bioactive peptides Inhibitor of tripeptidyl-peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090) according to BRENDA database Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02.006) according to AHTPDB database; BIOPEP database of bioactive peptides; BRENDA database; ChEMBL database; PubChem database Inhibitor of carboxypeptidase A (EC 3.4.17.1) (MEROPS ID: M14.001) according to BRENDA database Isolated from sake and sake byproducts Saito Y., Wanezaki K., Kawato A., Imayasu S., 1994, Antihypertensive effects of peptide in sake and its by-products on spontaneously antihypertensive rats. Biosci. Biotech. Biochem., 58, 812-816 Isolated from silk fibroin hydrolysate. Zhou F., Xue Z., Wang J., 2010, Antihypertensive effects of silk fibroin hydrolysate by alcalase and purification of an ACE inhibitory dipeptide. J. Agric. Food Chem., 58, 6735-6740 Found in amaranth (Amarantus hypochondriacus) proteins: Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111
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