BIOPEP-UWM: Report

ID 10
Name bitter peptide
sequence
FFF

Function:
(Rcaf) 5
 
Number of residues
3
Activity code
bi
Activity :
bitter
Chemical mass 459.5357 Monoisotopic mass 459.2151
EC50 :
0.00 µM



Bibliographic data:
Authors
Otagiri K., Nosho Y., Shinoda I., Fukui H., Okai H.
Title
Studies on a model bitter peptides including arginine, proline and phenylalanine residues. I. Bitter taste of di- and tripeptides and bitterness increase of the model peptides by extension of the peptide chain. Agric. Biol. Chem., 49, 1019-1026, 1985
Year Source
1985 Journal



Additional information:

BIOPEP database of sensory peptides and amino acids


SMILES: c1ccc(cc1)C[C@@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)O)N

InChI=1S/C27H29N3O4/c28-22(16-19-10-4-1-5-11-19)25(31)29-23(17-20-12-6-2-7-13-20)26(32)30-24(27(33)34)18-21-14-8-3-9-15-21/h1-15,22-24H,16-18,28H2,(H,29,31)(H,30,32)(H,33,34)/t22-,23-,24-/m0/s1

InChIKey: CBENHWCORLVGEQ-HJOGWXRNSA-N


Another reference for bitter taste:
Upadhyaya J., Pydi S. P., Singh N., Aluko R. E., Chelikani P., 2010, Bitter taste receptor T2R1 is activated by dipeptides and tripeptides. Biochem. Biophys. Res. Commun., 398, 331-335.

Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: XM02-001) according to AHTPDB database



Database reference:
ACToR: ID 2578-81-6

AHTPDB: ID 4573; 4851; 5487

BitterDB: ID 838

BRENDA: Ligand Phe-Phe-Phe

ChEMBL: ID CHEMBL420482

ChemSpider: ID 68256

PubChem: ID 75739