BIOPEP-UWM: Report

ID 106
Name bitter peptide
sequence
GV
Function:
(Rcaf) 0.22
 
Number of residues
2
Activity code
bi
Activity :
bitter
Chemical mass 174.1971 Monoisotopic mass 174.1001
EC50 :
0.00 µM


Bibliographic data:
Authors
Ishibashi N., Ono I., Kato K., Shigenaga T., Shinoda I., Okai H., Fukui S.
Title
Role of the hydrophobic amino acid residue in the bitterness of peptides. Agric. Biol. Chem., 52, 91-94, 1988
Year Source
1988 Journal


Additional information:
BIOPEP database of sensory peptides and amino acids


SMILES: NCC(=O)N[C@@H](C(C)C)C(=O)O

InChI=1S/C7H14N2O3/c1-4(2)6(7(11)12)9-5(10)3-8/h4,6H,3,8H2,1-2H3,(H,9,10)(H,11,12)/t6-/m0/s1

InChIKey: STKYPAFSDFAEPH-LURJTMIESA-N


Another references concerning bitterness:

Asao M., Iwamura H., Akamatsu M., Fujita T., 1987, Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives. J. Med. Chem., 30, 1873-1879

Collantes E. R., Dunn W. J., 1995, Amino acid side chain descriptors for quantitative structure-activity relationship studies of peptide analogues. J. Med. Chem., 38, 2705-2713


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001) according to AHTPDB database; BindingDB; BIOPEP database of bioactive peptides (ID 7608); ChEMBL database; EROP-Moscow database; PubChem database
Inhibitor of Dipeptidyl Peptidase IV (DPPIV) (EC 3.4.14.5) (MEROPS ID: S09.003) according to BIOPEP database of bioactive peptides (ID 8786)
Inhibitor of citrulline uptake in yeasts according to ChEMBL database; PubChem database


Database reference:
AHTPDB: ID 1429; 1689; 3021; 3026; 3098; 3119; 3140; 3160; 3241; 3333; 3423; 3811; 3837; 3936; 4412; 4517; 4680; 5435; 6170; 6594

BindingDB: ID 50407462

BIOPEP database of bioactive peptides: ID 7608; 8786

BRENDA: Ligand Gly-Val

ChEBI: ID 73922

ChEMBL: ID CHEMBL56035

ChemSpider: ID 2006926

Crystallography Open Database (COD): ID 2015750

EROP-Moscow: ID E10385

PubChem: ID 2724807

ZINC: ID ZINC01730674