BIOPEP-UWM: Report

ID 145
Name bitter peptide
sequence
AD
Function:
(Rcaf) 0.17
 
Number of residues
2
Activity code
bi
Activity :
bitter
Chemical mass 204.1801 Monoisotopic mass 204.0743
EC50 :
0.00 µM


Bibliographic data:
Authors
Ohyama S., Ishibashi N., Tamura M., Nishizaki H., Okai H.
Title
Synthesis of bitter peptides composed of aspartic acid and glutamic acid. Agric. Biol. Chem., 52, 871-872, 1988
Year Source
1988 Journal


Additional information:

BIOPEP-UWM database of sensory peptides and amino acids


SMILES: N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)O

InChI=1S/C7H12N2O5/c1-3(8)6(12)9-4(7(13)14)2-5(10)11/h3-4H,2,8H2,1H3,(H,9,12)(H,10,11)(H,13,14)/t3-,4-/m0/s1

InChIKey: XAEWTDMGFGHWFK-IMJSIDKUSA-N


Described as bitter/umami.

Another publication concerning peptide taste:

Kuramitsu R., Takahashi M., Tahara K., Nakamura K., Okai H., 1996, Tastes produced by peptides containing ionic groups and by related compounds. Biosci. Biotech. Biochem., 60, 1637-1642


Umami taste according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 449)

Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides
Inhibitor of alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides (ID 9695)


Database reference:
AHTPDB: ID 5444

BindingDB: ID 50188504

BioPepDB: ID biopep00005

BIOPEP-UWM database of bioactive peptides: ID 8757; 9695

BIOPEP-UWM database of sensory peptides and amino acids: ID 145; 449

BRENDA: Ligand Ala-Asp

ChEBI: ID 73803

ChEMBL: ID CHEMBL380047

ChemIDplus: ID 020727655

ChemSpider: ID 90094

J-GLOBAL: ID 200907057650534761

Metabolights: ID MTBLC73803

MetaCyc: Compound L-alanyl-L-aspartate

Nikkaji: ID J149.631J

PubChem: ID 99719

SATPdb: ID satpdb21143

SureChEMBL: ID SCHEMBL8648570

ZINC: ID ZINC000001731782