BIOPEP-UWM: Report

ID 161
Name bitter peptide
sequence
LG
Function:
(Rcaf) 0.05
 
Number of residues
2
Activity code
bi
Activity :
bitter
Chemical mass 188.2236 Monoisotopic mass 188.1157
EC50 :
0.00 µM


Bibliographic data:
Authors
Ishibashi N., Kouge K., Shinoda I., Kanehisa H., Okai H.
Title
A mechanism for bitter taste sensibility in peptides. Agric. Biol. Chem., 52, 819-827
Year Source
1988 Journal


Additional information:
BIOPEP database of sensory peptides and amino acids


SMILES: N[C@H](C(=O)NCC(=O)O)CC(C)C

InChI=1S/C8H16N2O3/c1-5(2)3-6(9)8(13)10-4-7(11)12/h5-6H,3-4,9H2,1-2H3,(H,10,13)(H,11,12)/t6-/m0/s1

InChIKey: LESXFEZIFXFIQR-LURJTMIESA-N


Another references concerning bitterness:

Asao M., Iwamura H., Akamatsu M., Fujita T., 1987, Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives. J. Med. Chem., 30, 1873-1879

Collantes E. R., Dunn W. J., 1995, Amino acid side chain descriptors for quantitative structure-activity relationship studies of peptide analogues. J. Med. Chem., 38, 2705-2713


Inhibitor of Leucyl aminopeptidase (EC 3.4.11.1) (MEROPS ID: M17.001) according to BRENDA database
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: XM02-001) according to AHTPDB database; Binding DB database; BIOPEP database of bioactive peptides; ChEMBL database; EROP-Moscow database; PubChem database
Inhibitor of Polar-amino-acid-transporting ATPase (EC 3.6.3.21) according to BRENDA database
Inhibitor of citrulline uptake in yeasts according to ChEMBL database; PubChem database


Database reference:
AHTPDB: ID 1489; 3045; 3051; 3086; 3132; 3134; 3136; 3251; 3355; 3426; 3515; 3822; 3851; 3977; 4401; 4528; 4654; 5406; 6606

BindingDB: ID 50407456

BIOPEP database of bioactive peptides: ID 7619

BRENDA: Ligand Leu-Gly

ChEBI: ID 74534

ChEMBL: ID CHEMBL55711

ChemIDplus: ID 000686500

ChemSpider: ID 87882

EROP-Moscow: ID E01614

PubChem: ID 97364

ZINC: ID ZINC02164045