BIOPEP-UWM: Report

ID 165
Name bitter peptide
sequence
GI

Function:
(Rcaf) 0.44
 
Number of residues
2
Activity code
bi
Activity :
bitter
Chemical mass 188.2236 Monoisotopic mass 188.1157
EC50 :
0.00 µM



Bibliographic data:
Authors
Ishibashi N., Kouge K., Shinoda I., Kanehisa H., Okai H.
Title
A mechanism for bitter taste sensibility in peptides. Agric. Biol. Chem., 52, 819-827, 1988
Year Source
1988 Journal



Additional information:
BIOPEP database of sensory peptides and amino acids


SMILES: NCC(=O)N[C@H](C(=O)O)[C@H](CC)C

InChI=1S/C8H16N2O3/c1-3-5(2)7(8(12)13)10-6(11)4-9/h5,7H,3-4,9H2,1-2H3,(H,10,11)(H,12,13)/t5-,7-/m0/s1

InChIKey: KGVHCTWYMPWEGN-FSPLSTOPSA-N


Another reference concerning bitterness:

Asao M., Iwamura H., Akamatsu M., Fujita T., 1987, Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives. J. Med. Chem., 30, 1873-1879


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to BIOPEP database of bioactive peptides (ID 8785)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001) according to AHTPDB database; BindingDB database; BIOPEP database of bioactive peptides (ID 7596); ChEMBL database; EROP-Moscow database; PubChem database
Inhibitor of citrulline uptake in yeasts according to ChEMBL database; PubChem database



Database reference:
AHTPDB: ID 1395; 1422; 1684; 3048; 3231; 3310; 3485; 3558; 3800; 3839; 3922; 4425; 4506; 4647; 5150; 5646; 6582

BindingDB: ID 50407465

BIOPEP database of bioactive peptides: ID 7596; 8785

BRENDA: Ligand Gly-Ile

ChEBI: ID 73907

ChEMBL: ID CHEMBL55433

ChemIDplus: ID 019461382

ChemSpider: ID 79464

EROP-Moscow: ID E10379

Metabolomics Workbench: ID 71583

PubChem: ID 88079

ZINC: ID ZINC01575508