BIOPEP-UWM: Report

ID 175
Name bitter peptide
sequence
LGG

Function:
(Rcaf) 0.01
 
Number of residues
3
Activity code
bi
Activity :
bitter
Chemical mass 245.2748 Monoisotopic mass 245.1371
EC50 :
0.00 µM



Bibliographic data:
Authors
Ishibashi N., Arita Y., Kanehisa H., Kouge K., Okai H., Fukui S.
Title
Bitterness of leucine-containing peptides. Agric. Biol. Chem., 51, 2389-2394, 1987
Year Source
1987 Journal



Additional information:
BIOPEP database of sensory peptides and amino acids


SMILES: N[C@H](C(=O)NCC(=O)NCC(=O)O)CC(C)C

InChI=1S/C10H19N3O4/c1-6(2)3-7(11)10(17)13-4-8(14)12-5-9(15)16/h6-7H,3-5,11H2,1-2H3,(H,12,14)(H,13,17)(H,15,16)/t7-/m0/s1

InChIKey: VWHGTYCRDRBSFI-ZETCQYMHSA-N


Another reference concerning bitterness:

Asao M., Iwamura H., Akamatsu M., Fujita T., 1987, Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives. J. Med. Chem., 30, 1873-1879


Inhibitor of citrulline uptake in yeasts according to ChEMBL database; PubChem database
Inhibitor of Tripeptide aminopeptidase (EC 3.4.11.4) (MEROPS ID: M20.003) according to BRENDA database
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: XM02-001) according to AHTPDB database
Inhibitor of Lactocepin (EC 3.4.21.96) (MEROPS ID: S08.019) according to BRENDA database
Inhibitor of Calicivirin (EC 3.4.22.66) (MEROPS ID: C24.001) according to BRENDA database



Database reference:
AHTPDB: ID 4547; 4833; 5461

BindingDB: ID 50169136

BRENDA: Ligand Leu-Gly-Gly

ChEBI: ID 74538

ChEMBL: ID CHEMBL297722

ChemIDplus: ID 001187504

ChemSpider: ID 64073

EROP-Moscow: ID E06288

PubChem: ID 70910

ZINC: ID ZINC01708209