BIOPEP-UWM: Report

ID 178
Name bitter peptide
sequence
LGL

Function:
(Rcaf) 0.2
 
Number of residues
3
Activity code
bi
Activity :
bitter
Chemical mass 301.3808 Monoisotopic mass 301.1995
EC50 :
0.00 µM



Bibliographic data:
Authors
Ishibashi N., Arita Y., Kanehisa H., Kouge K., Okai H., Fukui S.
Title
Bitterness of leucine-containing peptides. Agric. Biol. Chem., 51, 2389-2394, 1987
Year Source
1987 Journal



Additional information:
BIOPEP database of sensory peptides and amino acids


SMILES: N[C@H](C(=O)NCC(=O)N[C@H](C(=O)O)CC(C)C)CC(C)C

InChI=1S/C14H27N3O4/c1-8(2)5-10(15)13(19)16-7-12(18)17-11(14(20)21)6-9(3)4/h8-11H,5-7,15H2,1-4H3,(H,16,19)(H,17,18)(H,20,21)/t10-,11-/m0/s1

InChIKey: HYIFFZAQXPUEAU-QWRGUYRKSA-N


Another reference concerning bitterness:

Asao M., Iwamura H., Akamatsu M., Fujita T., 1987, Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives. J. Med. Chem., 30, 1873-1879


Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: XM02-001) according to AHTPDB database
Inhibitor of Penicillopepsin (EC 3.4.23.20) (MEROPS ID: A01.011) according to BRENDA database

Inhibitor of citrulline uptake in yeasts according to ChEMBL database; PubChem database



Database reference:
AHTPDB: ID 4551; 4835; 5465

BRENDA: Ligand Leu-Gly-Leu

ChEMBL: ID CHEMBL54363

ChemIDplus: ID 019408481

ChemSpider: ID 79432

PubChem: ID 88047

ZINC: ID ZINC01569740