BIOPEP-UWM: Report

ID 18
Name bitter peptide
sequence
FG
Function:
(Rcaf) 0.17
 
Number of residues
2
Activity code
bi
Activity :
bitter
Chemical mass 222.2399 Monoisotopic mass 222.1001
EC50 :
0.00 µM


Bibliographic data:
Authors
Otagiri K., Nosho Y., Shinoda I., Fukui H., Okai H.
Title
Studies on a model bitter peptides including arginine, proline and phenylalanine residues. I. Bitter taste of di- and tripeptides and bitterness increase of the model peptides by extension of the peptide chain. Agric. Biol. Chem., 49, 1019-1026, 1985
Year Source
1985 Journal


Additional information:
BIOPEP-UWM database of sensory peptides and amino acids


SMILES: N[C@H](C(=O)NCC(=O)O)Cc1ccccc1

InChI=1S/C11H14N2O3/c12-9(11(16)13-7-10(14)15)6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,16)(H,14,15)/t9-/m0/s1

InChiKey: GLUBLISJVJFHQS-VIFPVBQESA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database, the BIOPEP-UWM database of bioactive peptides (ID 7605); the EROP-Moscow database (ID E10395)
Inhibitor of Neprilysin (EC 3.4.24.11) (MEROPS ID: M13.001) according to the BRENDA database


Another references concerning peptide bitterness:

Maehashi K., Matano M., Wang H., Vo L. A., Yamamoto Y., Huang L., 2008, Bitter peptides activate hTAS2Rs, the human bitter receptors. Biochem. Biophys. Res. Commun., 365, 851–855

Upadhyaya J., Pydi S. P., Singh N., Aluko R. E., Chelikani P., 2010, Bitter taste receptor T2R1 is activated by dipeptides and tripeptides. Biochem. Biophys. Res. Commun., 398, 331-335


Database reference:
ACToR: ID 294-26-2

AHTPDB: ID 1483; 3058; 3144; 3238; 3479; 3809; 3876; 3907; 4415; 4515; 4674; 5412; 6591

BindingDB: ID 50139894

BioPepDB: ID biopep00236

BIOPEP-UWM database of bioactive peptides: ID 7605

BitterDB: ID 835

BRENDA: Ligand Phe-Gly

ChEBI: ID 73635

ChEMBL: ID CHEMBL417979

ChemSpider: ID 5360444

EROP-Moscow: ID E03702; E10395

FeptideDB: ID 7605

J-GLOBAL: ID 200907031969906344

MeSH: Term phenylalanylglycine; ID C040500

Metabolights: ID MTBLC73635

Nikkaji: ID J79.926B

PlantPepDB: ID PPepDB_2903

PubChem: CID 6992304

SATPdb: ID satpdb13141

SureChEMBL: ID SCHEMBL1329817

ZINC: ID ZINC01569733