BIOPEP-UWM: Report
| ID | 19 |
| Name | bitter peptide |
| sequence |
| Function: | |||
| (Rcaf) 0.83 | |||
| Number of residues | 2 |
Activity code | bi |
| Activity : | bitter |
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| Chemical mass | 222.2399 | Monoisotopic mass | 222.1001 | |
| EC50 : | 0.00 µM |
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| Bibliographic data: | |
| Authors | |
| Otagiri K., Nosho Y., Shinoda I., Fukui H., Okai H. | |
| Title | |
| Studies on a model bitter peptides including arginine, proline and phenylalanine residues. I. Bitter taste of di- and tripeptides and bitterness increase of the model peptides by extension of the peptide chain. Agric. Biol. Chem., 49, 1019-1026, 1985 | |
| Year | Source |
| 1985 | Journal |
| Additional information: |
| BIOPEP-UWM database of bitter peptides and amino acids SMILES: NCC(=O)N[C@H](C(=O)O)Cc1ccccc1 InChI=1S/C11H14N2O3/c12-7-10(14)13-9(11(15)16)6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,14)(H,15,16)/t9-/m0/s1 InChIKey: JBCLFWXMTIKCCB-VIFPVBQESA-N Other references concerning bitterness: Asao M., Iwamura H., Akamatsu M., Fujita T., 1987, Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives. J. Med. Chem., 30, 1873-1879 Collantes E. R., Dunn W. J., 1995, Amino acid side chain descriptors for quantitative structure-activity relationship studies of peptide analogues. J. Med. Chem., 38, 2705-2713 Maehashi K., Matano M., Wang H., Vo L. A., Yamamoto Y., Huang L., 2008, Bitter peptides activate hTAS2Rs, the human bitter receptors. Biochem. Biophys. Res. Commun., 365, 851-835 Upadhyaya J., Pydi S. P., Singh N., Aluko R. E., Chelikani P., 2010, Bitter taste receptor T2R1 is activated by dipeptides and tripeptides. Bitter taste receptor T2R1 is activated by dipeptides and tripeptides. Biochem. Biophys. Res. Commun., 398, 331-335 Keil B., Polonsky J., Nouaille F., Lederer E., 1978, Identification of the bitter principle of cocoa. Helv. Chim. Acta, 58, 1078-1086 Inhibitor of cholecystokinin-8-inactivating peptidase (tripeptidyl-peptidase II) (EC 3.4.14.10) (MEROPS ID: S08.090) according to BRENDA database, PubChem database Inhibitor of acylaminoacyl-peptidase (EC 3.4.19.1) (MEROPS ID: S09.004) according to BRENDA database Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 7591). Inhibitor of dipeptidyl-peptidase III (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9488), the BRENDA database Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8782) Antimalarial peptide according to the ParaPep database |
| Database reference: |
| ACToR: ID 3321-03-7 AHTPDB: ID 1112; 1383; 1402; 1421; 1681; 1813; 2657; 2791; 2936; 3023; 3176; 3483; 3796; 3841; 3918; 4232; 4430; 4502; 4697; 5149; 5427; 5455; 5744; 6577 BindingDB: ID 50188491 BioPepDB: ID biopep00334 BIOPEP-UWM database of bioactive peptides: ID 7591, 8782, 9488 BitterDB: ID 835 BRENDA: Ligand Gly-Phe ChEBI: ID 73912 ChEMBL: ID CHEMBL299889 ChemIDplus: ID 3321-03-7 ChemSpider: ID 83909 ECHA: compound N-glycyl-3-phenylalanine eChemPortal: ID 3321-03-7 EROP-Moscow: ID E03703; E09345 Golm Metabolome Database: ID M001062 J-GLOBAL: ID 200907093284113983 MassBank: ID MT000058 Metabolights: ID MTBLC73912 MetaCyc: compound glycyl-L-phenylalanine NIAID: ID 335273, 335277 Nikkaji: ID J149.622K NIST Webbook: compound Glycyl-L-phenyl alanine ParaPep: ID 1161 Pitt Quantum Repository: compound Glycyl-Phenylalanine PubChem: CID 92953 SATPdb: ID satpdb12994 SDBS: ID MS-NW-2034; NMR-CDS-03-391 ZINC: ID ZINC01569529 |