BIOPEP-UWM: Report

ID 190
Name bitter peptide
sequence
LV
Function:
(Rcaf) 0.17
 
Number of residues
2
Activity code
bi
Activity :
bitter
Chemical mass 230.3031 Monoisotopic mass 230.1625
EC50 :
0.00 µM


Bibliographic data:
Authors
Ishibashi N., Arita Y., Kanehisa H., Kouge K., Okai H., Fukui S.
Title
Bitterness of leucine-containing peptides. Agric. Biol. Chem., 51, 2389-2394, 1987
Year Source
1987 Journal


Additional information:
BIOPEP database of sensory peptides and amino acids


SMILES: N[C@H](C(=O)N[C@H](C(=O)O)C(C)C)CC(C)C

InChI=1S/C11H22N2O3/c1-6(2)5-8(12)10(14)13-9(7(3)4)11(15)16/h6-9H,5,12H2,1-4H3,(H,13,14)(H,15,16)/t8-,9-/m0/s1

InChIKey: MDSUKZSLOATHMH-IUCAKERBSA-N


Peptide found in whey protein hydrolysate:

Morifuji M., Koga J., Kawanaka K., Higuchi M., 2009, Branched-chain amino acid-containing dipeptides, identified from whey protein hydrolysates, stimulate glucose uptake in L6 myotubes and isolated skeletal muscles. J. Nutr. Sci. Vitaminol., 55, 81-86


Glucose uptake stimulating peptide according to BIOPEP database of bioactive peptides (ID 8321)
Inhibitor of citrulline uptake in yeasts according to ChEMBL database; PubChem database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to BIOPEP database of bioactive peptides (ID 8825)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001) according to AHTPDB database


Database reference:

AHTPDB: ID 5407

BIOPEP database of bioactive peptides: ID 8321; 8825

BRENDA: Ligand Leu-Val

ChEBI: ID 73579

ChEMBL: ID CHEMBL1222155

ChemSpider: ID 5361219

PubChem: ID 6993116

ZINC: ID ZINC01605717