BIOPEP-UWM: Report

ID 191
Name bitter peptide
sequence
LI
Function:
(Rcaf) 0.25
 
Number of residues
2
Activity code
bi
Activity :
bitter
Chemical mass 244.3296 Monoisotopic mass 244.1781
EC50 :
0.00 µM


Bibliographic data:
Authors
Ishibashi N., Arita Y., Kanehisa H., Kouge K., Okai H., Fukui S.
Title
Bitterness of leucine-containing peptides. Agric. Biol. Chem., 51, 2389-2394, 1987
Year Source
1987 Journal


Additional information:
BIOPEP database of sensory peptides and amino acids


SMILES: N[C@H](C(=O)N[C@H](C(=O)O)[C@H](CC)C)CC(C)C

InChI=1S/C12H24N2O3/c1-5-8(4)10(12(16)17)14-11(15)9(13)6-7(2)3/h7-10H,5-6,13H2,1-4H3,(H,14,15)(H,16,17)/t8-,9-,10-/m0/s1

InChIKey: AZLASBBHHSLQDB-GUBZILKMSA-N


Peptide found in whey protein hydrolysate:

Morifuji M., Koga J., Kawanaka K., Higuchi M., 2009, Branched-chain amino acid-containing dipeptides, identified from whey protein hydrolysates, stimulate glucose uptake in L6 myotubes and isolated skeletal muscles. J. Nutr. Sci. Vitaminol., 55, 81-86


Glucose uptake stimulator according to BIOPEP database of bioactive peptides (ID 8324); EROP-Moscow database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to BIOPEP database of bioactive peptides (ID 8821)
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: XM02-001) according to AHTPDB database
Inhibitor of citrulline uptake in yeasts according to ChEMBL database


Database reference:
AHTPDB: ID 5408

BIOPEP database of bioactive peptides: ID 8324; 8821

BRENDA: Ligand Leu-Ile

ChEBI: ID 74540

ChEMBL: ID CHEMBL1222322

ChemSpider: ID 5374100

EROP-Moscow: ID E10606

PubChem: ID 7010533

ZINC: ID ZINC02390960