BIOPEP-UWM: Report

ID 277
Name Umami peptide
sequence
DDE

Function:
 
Number of residues
3
Activity code
um
Activity :
umami
Chemical mass 377.3033 Monoisotopic mass 377.1065
EC50 :
0.00 µM



Bibliographic data:
Authors
Nakata T., Takahashi M., Nakatani M., Kuramitsu R., Tamura M., Okai H.
Title
Role of basic and acidic fragments in delicious peptides (Lys-Gly-Asp-Glu-Glu-Ser-Leu-Ala) and the taste behavior of sodium and potassium salts in acidic oligopeptides. Biosci. Biotech. Biochem., 59, 689-693, 1995
Year Source
1995 Journal



Additional information:
BIOPEP database of sensory peptides and amino acids


SMILES: N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CCC(=O)O)CC(=O)O)CC(=O)O

InChI=1S/C13H19N3O10/c14-5(3-9(19)20)11(23)16-7(4-10(21)22)12(24)15-6(13(25)26)1-2-8(17)18/h5-7H,1-4,14H2,(H,15,24)(H,16,23)(H,17,18)(H,19,20)(H,21,22)(H,25,26)/t5-,6-,7-/m0/s1

InChIKey: WCFCYFDBMNFSPA-ACZMJKKPSA-N


Annotated as umami/salty at pH 6

Nakata T., Takahashi M., Nakatani M., Kuramitsu R., Tamura M., Okai H., 1995, Role of basic and acidic fragments in delicious peptides (Lys-Gly-Asp-Glu-Glu-Ser-Leu-Ala) and the taste behavior of sodium and potassium salts in acidic oligopeptides. Biosci. Biotech. Biochem., 59, 689-693;

Another reference concerning umami taste:

Monastyrskaia K., Lundstrom K., Plahl D., Acuna G., Schweitzer C., Malherbe P., Mutel V., 1999, Effect of the umami peptides on the ligand binding and function of rat mGlu4a receptor might implicate this receptor in the monosodium glutamate taste transduction. Brit. J. Pharmacol., 128, 1027-1034

Salty peptide according to BIOPEP database of sensory peptides and amino acids (ID 278)




Database reference:
BIOPEP database of sensory peptides and amino acids: ID 278

ChemSpider: ID 8537660

PubChem: ID 10362211