BIOPEP-UWM: Report

ID 329
Name Bitter peptide
sequence
VG
Function:
Bitter taste
 
Number of residues
2
Activity code
bi
Activity :
bitter
Chemical mass 174.1971 Monoisotopic mass 174.1001
EC50 :
0.00 µM


Bibliographic data:
Authors
Asao M., Iwamura H., Akamatsu M., Fujita T.
Title
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives. J. Med. Chem., 30, 1873-1879, 1987
Year Source
1987 Journal


Additional information:
BIOPEP-UWM database of sensory peptides and amino acids


SMILES: N[C@@H](C(C)C)C(=O)NCC(=O)O

InChI=1S/C7H14N2O3/c1-4(2)6(8)7(12)9-3-5(10)11/h4,6H,3,8H2,1-2H3,(H,9,12)(H,10,11)/t6-/m0/s1

InChIKey: IOUPEELXVYPCPG-LURJTMIESA-N


Another reference concerning bitterness:
Collantes E. R., Dunn W. J., 1995, Amino acid side chain descriptors for quantitative structure-activity relationship studies of peptide analogues. J. Med. Chem., 38, 2705-2713

Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 7594); the BRENDA database; the ChEMBL database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8918)
Inhibitor of citrulline uptake in yeasts according to the ChEMBL database

Umami peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 258)


Database reference:
AHTPDB: ID 1274; 1477; 1682; 1895; 2750; 3008; 3012; 3034; 3038; 3041; 3122; 3127; 3157; 3345; 3542; 3587; 3605; 3798; 3847; 4038; 4427; 4504; 4702; 6214; 6580

BindingDB: ID 50407444

BioPepDB: ID biopep01364

BIOPEP-UWM database of bioactive peptides: ID 7594; 8918

BIOPEP-UWM database of sensory peptides and amino acids: ID 329

BRENDA: Ligand Val-Gly

ChEBI: ID 73699

ChEMBL: ID CHEMBL301546

ChemIDplus: ID 686-43-1

ChemSpider: ID 5361214

EPA CompTox: ID DTXSID50879006

EPA DSSTox: ID DTXCID601017026

EROP-Moscow: ID E01603

FeptideDB: ID 7594; 8918

FooDB: ID FDB112129

HMDB: ID HMDB0029127

J-GLOBAL: ID 200907061082081770

Metabolights: ID MTBLC73699

Nikkaji: ID J149.649B

PlanPepDB: ID PPepDB_201

PubChem: ID 6993110

SATPdb: ID satpdb16642

SDBS: ID 4377

SureChEMBL: ID SCHEMBL2782029

ZINC: ID ZINC000001605643