BIOPEP-UWM: Report

ID 344
Name Bitter peptide
sequence
YPFPGPIHNS

Function:
Rcaf = 20
 
Number of residues
10
Activity code
bi
Activity :
bitter
Chemical mass 1128.2332 Monoisotopic mass 1127.5383
EC50 :
0.00 µM



Bibliographic data:
Authors
Toelstede S., Hofmann T.
Title
Sensomics mapping and identification of the key bitter metabolites in Gouda cheese. J. Agric. Food. Chem., 56, 2795-2804
Year Source
2008 Journal



Additional information:
BIOPEP database of sensory peptides and amino acids


SMILES: N[C@H](C(=O)N1[C@H](C(=O)N[C@H](C(=O)N2[C@H](C(=O)NCC(=O)N3[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CO)CC(=O)N)Cc4[nH]cnc4)[C@H](CC)C)CCC3)CCC2)Cc2ccccc2)CCC1)Cc1ccc(cc1)O

InChI=1S/C54H73N13O14/c1-3-30(2)45(51(77)61-36(24-33-26-57-29-59-33)46(72)60-37(25-43(56)70)47(73)63-39(28-68)54(80)81)64-50(76)41-13-7-19-65(41)44(71)27-58-48(74)40-12-8-21-67(40)53(79)38(23-31-10-5-4-6-11-31)62-49(75)42-14-9-20-66(42)52(78)35(55)22-32-15-17-34(69)18-16-32/h4-6,10-11,15-18,26,29-30,35-42,45,68-69H,3,7-9,12-14,19-25,27-28,55H2,1-2H3,(H2,56,70)(H,57,59)(H,58,74)(H,60,72)(H,61,77)(H,62,75)(H,63,73)(H,64,76)(H,80,81)/t30-,35-,36-,37-,38-,39-,40-,41-,42-,45-/m0/s1

InChIKey: UTLIMBWJQYIFTF-BGTRFFRESA-N


Another reference concerning bitterness:

Kohl S., Behrens M., Dunkel A., Hofmann T., Meyerhof W., 2013, Amino acids and peptides activate at least five members of the human bitter taste receptor family. J. Agric. Food Chem., 61, 53-60



Database reference:
PepBank: Peptide YPFPGPIHNS