BIOPEP-UWM: Report

ID 347
Name Bitter peptide
sequence
PL
Function:
Bitter taste
 
Number of residues
2
Activity code
bi
Activity :
bitter
Chemical mass 228.2873 Monoisotopic mass 228.1469
EC50 :
0.00 µM


Bibliographic data:
Authors
Asao M., Iwamura H., Akamatsu M., Fujita T.
Title
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives. J. Med. Chem., 30, 1873-1879, 1987
Year Source
1987 Journal


Additional information:
BIOPEP-UWM database of sensory peptides and amino acids


SMILES: N1[C@H](C(=O)N[C@H](C(=O)O)CC(C)C)CCC1

InChI=1S/C11H20N2O3/c1-7(2)6-9(11(15)16)13-10(14)8-4-3-5-12-8/h7-9,12H,3-6H2,1-2H3,(H,13,14)(H,15,16)/t8-,9-/m0/s1

InChIKey: ZKQOUHVVXABNDG-IUCAKERBSA-N


Another reference concerning bitterness:

Collantes E. R., Dunn W. J., 1995, Amino acid side chain descriptors for quantitative structure-activity relationship studies of peptide analogues. J. Med. Chem., 38, 2705-2713


Inhibitof of Xaa-Pro aminopeptidase (EC 3.4.11.9) (MEROPS ID: M24.005) according to BRENDA database; MMDB database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to BIOPEP-UWM database of bioactive peptides (ID 8638); BRENDA database
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to AHTPDB database; BIOPEP-UWM database of bioactive peptides (ID = 7513); BRENDA database; SATPdb database
Inhibitor of Lactocepin (EC 3.4.21.96) (MEROPS ID: S08.019) according to BRENDA database


Database reference:
AHTPDB: ID 3017; 3074; 3154; 3213; 3330; 3414; 3525; 3578; 3872; 4004; 6523

BindingDB: ID 50188501

BIOPEP-UWM database of bioactive peptides: ID 7513; 8638

BRENDA: Ligand Pro-Leu

ChEBI: ID 74791

ChEMBL: ID CHEMBL293494

ChemSpider: ID 392116

EROP-Moscow: ID E10409

FeptideDB: ID 7513; 8638

J-GLOBAL: ID 200907096179362578

Metabolights: ID MTBLC74791

MMDB: ID 9729; 34984; 35323

Nikkaji: ID J366.499F

PlanPepDB: ID PPepDB_2933

PubChem: ID 444109

SATPdb: ID satpdb27845

SureChEMBL: ID SCHEMBL6373762

ZINC: ID ZINC000004040320