BIOPEP-UWM: Report

ID 348
Name Bitter amino acid
sequence
W

Function:
Bitter taste
 
Number of residues
1
Activity code
bi
Activity :
bitter
Chemical mass 204.2247 Monoisotopic mass 204.0896
EC50 :
0.00 µM



Bibliographic data:
Authors
Solms J., Vuataz L., Egli R. H.
Title
The taste of L- and D-amino acids. Experientia, XXI, 692-694
Year Source
1965 Journal



Additional information:
BIOPEP database of sensory peptides and amino acids


SMILES: c1ccc2c(c1)c(c[nH]2)C[C@@H](C(=O)O)N

InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1

InChIKey: QIVBCDIJIAJPQS-VIFPVBQESA-N


Another references concerning bitterness:

Asao M., Iwamura H., Akamatsu M., Fujita T., 1987, Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives. J. Med. Chem., 30, 1873-1879


Kohl S., Behrens M., Dunkel A., Hofmann T., Meyerhof W., 2013, Amino acids and peptides activate at least five members of the human bitter taste receptor family. J. Agric. Food Chem., 61, 53-60



Database reference:
BindingDB: ID 21974

Biological Magnetic Resonance Data Bank: ID bmse000050

BitterDB: ID 827

BRENDA: Ligand Trp

ChEBI: ID 16828

ChEMBL: ID CHEMBL54976

ChemIDplus: ID 000073223

ChemSpider: ID 6066

DrugBank: ID DB00150

FooDB: Compound L-Tryptophan (ID FDB002250)

Golm Metabolome Database: 151A3008-4CFE-40C9-AC0B-467EF0CB50EA

Human Metabolome Database (HMDB): ID HMDB00929

KEGG: Compound C00078

MetaCyc: Compound L-tryptophan

MMDB: ID 19178; 19712; 16283; 16022; 17039; 18896; 18897; 10065; 11163; 2380

PubChem: ID 6305

ZINC: ID ZINC00083315