BIOPEP-UWM: Report

ID 349
Name Umami peptide
sequence
AE

Function:
Umami taste; detection threshold 1.5 mM
 
Number of residues
2
Activity code
um
Activity :
umami
Chemical mass 218.2066 Monoisotopic mass 218.0899
EC50 :
0.00 µM



Bibliographic data:
Authors
Ohyama S., Ishibashi N., Tamura M., Nishizaki H., Okai H.
Title
Synthesis of bitter peptides composed of aspartic acid and glutamic acid. Agric. Biol. Chem., 52, 871-872, 1988
Year Source
1988 Journal



Additional information:
BIOPEP database of sensory peptides and amino acids


SMILES: N[C@H](C(=O)N[C@H](C(=O)O)CCC(=O)O)C

InChI=1S/C8H14N2O5/c1-4(9)7(13)10-5(8(14)15)2-3-6(11)12/h4-5H,2-3,9H2,1H3,(H,10,13)(H,11,12)(H,14,15)/t4-,5-/m0/s1

InChIKey: VYZAGTDAHUIRQA-WHFBIAKZSA-N


First reference concerning umami taste;
Noguchi M., Arai S., Yamashita M., Kato H., Fujimaki M., 1975, Isolation and identification of acidic oligopeptides occurring in a flavor potentiating fraction from a fish protein hydrolysate. J. Agric. Food Chem., 23, 49-53

Reported as tasteless:
van den Oord A. H. A., van Wassenaar P. D. 1997, Umami peptides: assessment of their alleged taste properties. Z. Lebensm. Unters. Forsch., 205, 125-130


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP database of bioactive peptides
Inhibitor of Glutamate carboxypeptidase (EC 3.4.17.11) (MEROPS ID: M20.001) according to the BRENDA database
Inhibitor of Glutamate carboxypeptidase II (EC 3.4.17.21) (MEROPS ID: M28.010) according to the BRENDA database



Database reference:
BIOPEP database of bioactive peptides: ID 8758

BRENDA: Ligand Ala-Glu

ChEBI: ID 61565

ChEMBL: ID CHEMBL2074938

ChemIDplus: ID 013187901

ChemSpider: ID 114174

EROP-Moscow: ID E01841

PubChem: ID 128841

ZINC: ID ZINC02242980