BIOPEP-UWM: Report

ID 36
Name bitter peptide
sequence
GGY

Function:
(Rcaf) 0.67
 
Number of residues
3
Activity code
bi
Activity :
bitter
Chemical mass 295.2905 Monoisotopic mass 295.1164
EC50 :
0.00 µM



Bibliographic data:
Authors
Ishibashi N., Sadamori K., Yamamoto O., Kanehisa H., Kouge K., Kikuchi E., Okai H., Fukui S.
Title
Bitterness of phenylalanine- and tyrosine-containing peptides. Agric. Biol. Chem., 51, 3309-3313, 1987
Year Source
1987 Journal



Additional information:
BIOPEP database of sensory peptides and amino acids


SMILES: NCC(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

InChI=1S/C13H17N3O5/c14-6-11(18)15-7-12(19)16-10(13(20)21)5-8-1-3-9(17)4-2-8/h1-4,10,17H,5-7,14H2,(H,15,18)(H,16,19)(H,20,21)/t10-/m0/s1

InChIKey: INLIXXRWNUKVCF-JTQLQIEISA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001) according to AHTPDB database; BIOPEP database of bioactive peptides; EROP-Moscow database
Inhibitor of citrulline uptake in yeasts according to ChEMBL database


Peptide found in sake and sake by-products.
Saito Y., Wanezaki K., Kawato A., Imayasu S., 1994, Structure and activity of angiotensin I converting enzyme inhibitory peptides from sake and sake lees. Biosci. Biotech. Biochem., 58, 1767-1771

Peptide found in amaranth protein hydrolysate.
Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111



Database reference:

AHTPDB: ID 1137; 1593; 3484; 3920; 4562; 4862; 5476; 5588; 6434

BIOPEP database of bioactive peptides: ID 3515

BRENDA: Ligand Gly-Gly-L-Tyr

ChEMBL: ID CHEMBL1221778

ChemSpider: ID 5360628

EROP-Moscow: ID E09243

PubChem: ID 6992498

ZINC: ID ZINC01576190