BIOPEP-UWM: Report

ID 379
Name Bitter peptide
sequence
GPFPVI

Function:
Bitter peptide identified in tryptic hydrolysate of casein. Showed the bitterness in 0.1% water solution. The bitterness of GPFPVI was identical as in 0.1% phenylalanine water solution.
 
Number of residues
6
Activity code
bi
Activity :
bitter
Chemical mass 628.7576 Monoisotopic mass 628.3573
EC50 :
0.00 µM



Bibliographic data:
Authors
Matoba T., Hata T.
Title
Relationship between bitterness of peptides and their chemical structures. Agric Biol. Chem. 36, 1423 – 1431, 1972.
Year Source
1972 Journal



Additional information:
BIOPEP database of sensory peptides and amino acids


SMILES: NCC(=O)N1[C@H](C(=O)N[C@H](C(=O)N2[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)[C@H](CC)C)C(C)C)CCC2)Cc2ccccc2)CCC1

InChI=1S/C32H48N6O7/c1-5-20(4)27(32(44)45)36-30(42)26(19(2)3)35-29(41)24-14-10-16-38(24)31(43)22(17-21-11-7-6-8-12-21)34-28(40)23-13-9-15-37(23)25(39)18-33/h6-8,11-12,19-20,22-24,26-27H,5,9-10,13-18,33H2,1-4H3,(H,34,40)(H,35,41)(H,36,42)(H,44,45)/t20-,22-,23-,24-,26-,27-/m0/s1

InChIKey: PCGNLGAMFFODMW-PQJTZWKESA-N


First reference concerning bitterness:
Matoba T., Nagayashi C., Hayashi R., Hata T., 1969, Bitter peptides in tryptic hydrolysate of casein. Agric. Biol. Chem., 33, 1662-1663




Database reference:
EROP-Moscow: ID E01835