BIOPEP-UWM: Report

ID 45
Name bitter peptide
sequence
FP
Function:
(Rcaf) 0.67
 
Number of residues
2
Activity code
bi
Activity :
bitter
Chemical mass 262.3036 Monoisotopic mass 262.1313
EC50 :
0.00 µM


Bibliographic data:
Authors
Ishibashi N., Sadamori K., Yamamoto O., Kanehisa H., Kouge K., Kikuchi E., Okai H., Fukui S.
Title
Bitterness of phenylalanine- and tyrosine-containing peptides. Agric. Biol. Chem., 51, 3309-3313, 1987
Year Source
1987 Journal


Additional information:

BIOPEP database of sensory peptides and amino acids


SMILES: N[C@H](C(=O)N1[C@H](C(=O)O)CCC1)Cc1ccccc1

InChI=1S/C14H18N2O3/c15-11(9-10-5-2-1-3-6-10)13(17)16-8-4-7-12(16)14(18)19/h1-3,5-6,11-12H,4,7-9,15H2,(H,18,19)/t11-,12-/m0/s1

InChIKey: WEQJQNWXCSUVMA-RYUDHWBXSA-N


Found in amaranth (Amarantus hypochondriacus) proteins: Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001) according to the AHTPDB database; the BIOPEP database of bioactive peptides (ID 3502); the EROP-Moscow database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP database of bioactive peptides (ID 8506); the BRENDA database; the EROP-Moscow database
Antifungal peptide according to EROP-Moscow database


Database reference:
AHTPDB: ID 1135; 1334; 1366; 1664; 1743; 2580; 3181; 3204; 3396; 3556; 3596; 3878; 3909; 4071; 4161; 4728; 4949; 5147; 5417; 5565; 5585; 5702; 5948; 6421; 6865

BIOPEP database of bioactive peptides: ID 3502; 8506

BRENDA: Ligand Phe-Pro

ChEBI: ID 74750

ChEMBL: ID CHEMBL1807686

ChemSpider ID: 5383590

EROP-Moscow: ID E04808; E01602; E03693; E09206

PubChem: ID 7020641

ZINC: ID ZINC02392313