BIOPEP-UWM: Report

ID 457
Name Bitter peptide
sequence
FLL
Function:
Bitter peptide. Q value (i. e. average amount of free energy needed to transfer amino acid chains from ethanol to water) = 10449.9 J / (Mol x res).
 
Number of residues
3
Activity code
bi
Activity :
bitter
Chemical mass 391.5031 Monoisotopic mass 391.2463
EC50 :
0.00 µM


Bibliographic data:
Authors
Lemieux L., Simard R. E.
Title
Bitter flavour in dairy products. II. A review of bitter peptides from caseins: their formation, isolation and identification, structure masking and inhibition. Lait, 72, 335-382, 1992
Year Source
1992 Journal


Additional information:
BIOPEP database of sensory peptides and amino acids


SMILES: N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCSC)C(=O)N1CCC[C@@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

InChI=1S/C64H99N15O16S/c1-9-36(6)52(78-60(91)49-18-14-27-79(49)62(93)43(25-28-96-8)72-59(90)47(33-51(82)83)74-54(85)41(65)17-13-26-69-64(67)68)61(92)71-42(23-24-50(66)81)55(86)70-37(7)53(84)73-46(31-38-15-11-10-12-16-38)58(89)76-44(29-34(2)3)56(87)75-45(30-35(4)5)57(88)77-48(63(94)95)32-39-19-21-40(80)22-20-39/h10-12,15-16,19-22,34-37,41-49,52,80H,9,13-14,17-18,23-33,65H2,1-8H3,(H2,66,81)(H,70,86)(H,71,92)(H,72,90)(H,73,84)(H,74,85)(H,75,87)(H,76,89)(H,77,88)(H,78,91)(H,82,83)(H,94,95)(H4,67,68,69)/t36-,37-,41-,42-,43-,44-,45-,46-,47-,48-,49+,52-/m0/s1

InChIKey: BKUWUNPVMSQIRT-PXTKKBOVSA-N


Previous reference concerning peptide:

Monnet V., Le Bars D., Gripon J. C., 1986, Specificity of a cell Wall proteinase from Streptococcus lactis NCDO763 towards bovine beta-casein. FEMS Microbiol. Lett., 36, 127-131


Database reference:
BindingDB: ID 50169116

ChEMBL: ID CHEMBL190933

ChemSpider: ID 23257239

J-GLOBAL: ID 200907069549524176

Nikkaji: ID J1.333.067K

PubChem: ID 44398636