BIOPEP-UWM: Report

ID 472
Name Bitter peptide
sequence
PA

Function:
Bitter peptide
 
Number of residues
2
Activity code
bi
Activity :
bitter
Chemical mass 186.2078 Monoisotopic mass 186.1001
EC50 :
0.00 µM



Bibliographic data:
Authors
Asao M., Iwamura H., Akamatsu M., Fujita T.
Title
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives. J. Med. Chem., 1987, 30, 1873-1879
Year Source
1987 Journal



Additional information:
BIOPEP database of sensory peptides and amino acids


SMILES: N1[C@@H](CCC1)C(=O)N[C@@H](C)C(=O)O

InChI=1S/C8H14N2O3/c1-5(8(12)13)10-7(11)6-3-2-4-9-6/h5-6,9H,2-4H2,1H3,(H,10,11)(H,12,13)/t5-,6-/m0/s

InChIKey: FELJDCNGZFDUNR-WDSKDSINSA-N


Another reference concerning bitterness:
Collantes E. R., Dunn W. J ., 1995, Amino acid side chain descriptors for quantitative structure-activity relationship studies of peptide analogues. J. Med. Chem., 38, 2705-2713


Inhibitor of Membrane dipeptidase (EC 3.4.13.19) (MEROPS ID: M19.011) according to the BRENDA database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP database of sensory peptides and amino acids; the BRENDA database
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: XM02-001) according to the AHTPDB database



Database reference:
AHTPDB: ID 3871

BIOPEP database of bioactive peptides: ID 3179

BRENDA: Ligand Pro-Ala

ChEBI: ID 74753

ChEMBL: ID CHEMBL293555

ChemSpider: ID 4894114

EROP-Moscow: ID E09231

J-GLOBAL: ID 200907046022308050

Nikkaji: ID J149.647F

PubChem: ID 6347578

SATPdb: ID satpdb21841

SureChEMBL: ID SCHEMBL2841482

ZINC: ID ZINC04038298