BIOPEP-UWM: Report

ID 486
Name Bitter peptide
sequence
IA
Function:
Bitter taste
 
Number of residues
2
Activity code
bi
Activity :
bitter
Chemical mass 202.2501 Monoisotopic mass 202.1313
EC50 :
0.00 µM


Bibliographic data:
Authors
Asao M., Iwamura H., Akamatsu M., Fujita T.
Title
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives. J. Med. Chem., 30, 1873-1879, 1987
Year Source
1987 Journal


Additional information:
BIOPEP-UWM database of sensory peptides and amino acids


SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(C)C(=O)O

InChI=1S/C9H18N2O3/c1-4-5(2)7(10)8(12)11-6(3)9(13)14/h5-7H,4,10H2,1-3H3,(H,11,12)(H,13,14)/t5-,6-,7-/m0/s1

InChIKey=RCFDOSNHHZGBOY-ACZMJKKPSA-N


Another reference concerning bitterness:
Collantes E. R., Dunn W. J., 1995, Amino acid side chain descriptors for quantitative structure-activity relationship studies of peptide analogues. J. Med. Chem., 38, 2705-2713

Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8525); the EROP-Moscow database
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 7562); the EROP-Moscow database


Database reference:
ACToR: ID 24787-73-3

AHTPDB: ID 1462, 1848, 2666, 3116, 3218, 3307, 3499, 3858, 3944, 4059, 6548

BioPepDB: ID biopep00479

BIOPEP-UWM database of bioactive peptides: ID 7562; 8525

BRENDA: Ligand Ile-Ala

ChEBI: ID 74062

ChEMBL: ID CHEMBL54834

ChemSpider: ID 5373156

Crystallography Open Database (COD): ID 4101261

EPA CompTox: ID DTXSID60426565

EPA DSSTox: ID DTXCID90377399

EROP-Moscow: ID E09322

FeptideDB: ID 7562; 8525

J-GLOBAL: ID 200907023736200430

Metabolights: ID MTBLC74062

MMDB: ID 135413

Nikkaji: ID J1.992.204I

PlantPepDB: ID PPepDB_3008

PubChem: CID 7009577

SATPdb: ID satpdb23299

SureChEMBL: ID SCHEMBL8723097

ZINC: ID ZINC000002384798