BIOPEP-UWM: Report

ID 487
Name Bitter peptide
sequence
IE
Function:
Bitter taste
 
Number of residues
2
Activity code
bi
Activity :
bitter
Chemical mass 260.2861 Monoisotopic mass 260.1367
EC50 :
0.00 µM


Bibliographic data:
Authors
Asao M., Iwamura H., Akamatsu M., Fujita T.
Title
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives. J. Med. Chem., 30, 1873-1879, 1987
Year Source
1987 Journal


Additional information:
BIOPEP-UWM database of sensory peptides and amino acids


SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)O

InChI=1S/C11H20N2O5/c1-3-6(2)9(12)10(16)13-7(11(17)18)4-5-8(14)15/h6-7,9H,3-5,12H2,1-2H3,(H,13,16)(H,14,15)(H,17,18)/t6-,7-,9-/m0/s1

InChIKey=KTGFOCFYOZQVRJ-ZKWXMUAHSA-N


Another reference concerning bitterness:
Collantes E. R., Dunn W. J., 1995, Amino acid side chain descriptors for quantitative structure-activity relationship studies of peptide analogues. J. Med. Chem., 38, 2705-2713

Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 7827)
Inhibitor of Glutamate carboxypeptidase (EC 3.4.17.11) (MEROPS ID: M20.001) according to the BRENDA database


Database reference:
AHTPDB: ID 1701, 2987, 3033, 3113, 3280, 3356, 3437, 3867, 3946, 6730

BioPepDB: ID biopep00496

BIOPEP-UWM database of bioactive peptides: ID 7827

BRENDA: Ligand Ile-Glu

ChEBI: ID 137259

ChEMBL: ID CHEMBL436551

ChemSpider: ID 5373205

EROP-Moscow: ID E01850

FeptideDB: ID 7827

J-GLOBAL: ID 201407086499305160

Nikkaji: ID J3.318.463H

PubChem: CID 7009625

SATPdb: ID satpdb19205

SureChEMBL: ID SCHEMBL12496193

ZINC: ID ZINC000002384845