BIOPEP-UWM: Report

ID 488
Name Bitter peptide
sequence
IN

Function:
Bitter taste
 
Number of residues
2
Activity code
bi
Activity :
bitter
Chemical mass 245.2748 Monoisotopic mass 245.1371
EC50 :
0.00 µM



Bibliographic data:
Authors
Asao M., Iwamura H., Akamatsu M., Fujita T.
Title
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives. J. Med. Chem., 30, 1873-1879, 1987
Year Source
1987 Journal



Additional information:
BIOPEP-UWM database of sensory peptides and amino acids


SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)O

InChI=1S/C10H19N3O4/c1-3-5(2)8(12)9(15)13-6(10(16)17)4-7(11)14/h5-6,8H,3-4,12H2,1-2H3,(H2,11,14)(H,13,15)(H,16,17)/t5-,6-,8-/m0/s1

InChIKey=HZYHBDVRCBDJJV-HAFWLYHUSA-N


Another reference concerning bitterness:
Collantes E. R., Dunn W. J., 1995, Amino acid side chain descriptors for quantitative structure-activity relationship studies of peptide analogues. J. Med. Chem., 38, 2705-2713

Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8804)
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database



Database reference:
AHTPDB: ID 3864

BioPepDB: ID biopep00546

BIOPEP-UWM database of bioactive peptides: ID 8804

CHEBI: ID 74063

ChEMBL: ID CHEMBL55004

ChemSpider: ID 5379101

FeptideDB: ID 8804

Metabolights: ID MTBLC74063

PubChem: CID 7016080

SATPdb: ID satpdb15115

SureChEMBL: ID SCHEMBL9437463

ZINC: ID ZINC000002522618