BIOPEP-UWM: Report

ID 490
Name Bitter peptide
sequence
IQ
Function:
Bitter taste
 
Number of residues
2
Activity code
bi
Activity :
bitter
Chemical mass 259.3013 Monoisotopic mass 259.1527
EC50 :
0.00 µM


Bibliographic data:
Authors
Asao M., Iwamura H., Akamatsu M., Fujita T.
Title
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives. J. Med. Chem., 30, 1873-1879, 1987
Year Source
1987 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)O

InChI=1S/C11H21N3O4/c1-3-6(2)9(13)10(16)14-7(11(17)18)4-5-8(12)15/h6-7,9H,3-5,13H2,1-2H3,(H2,12,15)(H,14,16)(H,17,18)/t6-,7-,9-/m0/s1

InChIKey=CNPNWGHRMBQHBZ-ZKWXMUAHSA-N


Another reference concerning bitterness:
Collantes E. R., Dunn W. J., 1995, Amino acid side chain descriptors for quantitative structure-activity relationship studies of peptide analogues. J. Med. Chem., 38, 2705-2713

Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8805)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database


Database reference:
AHTPDB: ID 3866

BioPepDB: ID biopep00571

BIOPEP-UWM database of bioactive peptides: ID 8805

ChEBI: ID 74065

ChEMBL: ID CHEMBL55660

ChemSpider: ID 5383058

EROP-Moscow: ID E01609

FeptideDB: ID 8805

Metabolights: ID MTBLC74065

PubChem: CID 7020102

SATPdb: ID satpdb14532

SureChEMBL: ID SCHEMBL2488717

ZINC: ID ZINC000002561059