BIOPEP-UWM: Report

ID 5
Name bitter peptide
sequence
PP

Function:
(Rcaf) 0.22
 
Number of residues
2
Activity code
bi
Activity :
bitter
Chemical mass 212.2450 Monoisotopic mass 212.1157
EC50 :
0.00 µM



Bibliographic data:
Authors
Otagiri K., Nosho Y., Shinoda I., Fukui H., Okai H.
Title
Studies on a model bitter peptides including arginine, proline and phenylalanine residues. I. Bitter taste of di- and tripeptides and bitterness increase of the model peptides by extension of the peptide chain. Agric. Biol. Chem., 49, 1019-1026, 1985
Year Source
1985 Journal



Additional information:
BIOPEP database of sensory peptides and amino acids


SMILES: C1C[C@@H](C(=O)N2CCC[C@H]2C(=O)O)NC1

InChI=1S/C10H16N2O3/c13-9(7-3-1-5-11-7)12-6-2-4-8(12)10(14)15/h7-8,11H,1-6H2,(H,14,15)/t7-,8-/m0/s1

InChIKey: RWCOTTLHDJWHRS-YUMQZZPRSA-N


Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: XM02-001) according to AHTPDB database, BIOPEP database of bioactive peptides (ID 7836), EROP-Moscow database (ID E01865)
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to BIOPEP database of bioactive peptides (ID 3170)


Peptide found in milk hydrolysates.
van Platerink C. J., Janssen H.-G. M., Haverkamp J., 2008, Application of at-line two-dimensional liquid chromatography-mass spectrometry for identification of small hydrophilic angiotensin I-inhibiting peptides in milk hydrolysates. Anal. Bioanal. Chem., 2008, 391, 299-307



Database reference:

AHTPDB: ID 3007; 3289; 3445; 3527; 3579; 4007; 5442; 6739

BIOPEP database of bioactive peptides: ID 3170; 7836

BRENDA: Ligand Pro-Pro

ChEBI: ID 73646

ChEMBL: ID CHEMBL371194

ChemSpider: ID 9797341

EROP-Moscow: ID E01865; E09232

PubChem: ID 11622593

ZINC: ID ZINC04899613