BIOPEP-UWM: Report

ID 50
Name bitter peptide
sequence
AF
Function:
(Rcaf) 0.08
 
Number of residues
2
Activity code
bi
Activity :
bitter
Chemical mass 236.2664 Monoisotopic mass 236.1157
EC50 :
0.00 µM


Bibliographic data:
Authors
Ishibashi N., Sadamori K., Yamamoto O., Kanehisa H., Kouge K., Kikuchi E., Okai H., Fukui S.
Title
Bitterness of phenylalanine- and tyrosine-containing peptides. Agric. Biol. Chem., 51, 3309-3313, 1987
Year Source
1987 Journal


Additional information:
BIOPEP database of sensory peptides and amino acids


SMILES: N[C@H](C(=O)N[C@H](C(=O)O)Cc1ccccc1)C

InChI=1S/C12H16N2O3/c1-8(13)11(15)14-10(12(16)17)7-9-5-3-2-4-6-9/h2-6,8,10H,7,13H2,1H3,(H,14,15)(H,16,17)/t8-,10-/m0/s1

InChiKey: OMNVYXHOSHNURL-WPRPVWTQSA-N


Another references concerning bitterness:

Asao M., Iwamura H., Akamatsu M., Fujita T., 1987, Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives. J. Med. Chem., 30, 1873-1879

Collantes E. R., Dunn W. J., 1995, Amino acid side chain descriptors for quantitative structure-activity relationship studies of peptide analogues. J. Med. Chem., 38, 2705-2713


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001) according to AHTPDB database; BIOPEP database of bioactive peptides; BRENDA database; ChEMBL database; EROP-Moscow database (ID E03700)
Inhibitor of Tripeptidyl peptidase 2 (EC 3.4.14.10) (MEROPS ID S08.090 ) according to ChEMBL database


Database reference:
AHTPDB: ID 1271; 1363; 1410; 1503; 1678; 1892; 1896; 2591; 2747; 3031; 3222; 3344; 3419; 3465; 3790; 3846; 3886; 4441; 4496; 4679; 5429; 5787; 6211; 6569

BIOPEP database of bioactive peptides: ID 7583

BRENDA: Ligand Ala-Phe

ChEBI: ID 73807

ChEMBL: ID CHEMBL57338

ChemIDPlus: ID 3061-90-3

ChemSpider ID: 87414

EROP-Moscow: ID E04069; E03700

PubChem: ID 6992394

ZINC: ID ZINC01575524