BIOPEP-UWM: Report

ID 72
Name bitter peptide
sequence
VYP
Function:
(Rcaf) 0.33
 
Number of residues
3
Activity code
bi
Activity :
bitter
Chemical mass 377.4337 Monoisotopic mass 377.1944
EC50 :
0.00 µM


Bibliographic data:
Authors
Ishibashi N., Kubo T., Chino M., Fukui H., Shinoda I., Kikuchi E., Okai H., Fukui S.
Title
Taste of proline-containing peptides. Agric. Biol. Chem., 52, 95-98, 1988
Year Source
1988 Journal


Additional information:
BIOPEP database of sensory peptides and amino acids


SMILES: N[C@H](C(=O)N[C@H](C(=O)N1[C@H](C(=O)O)CCC1)Cc1ccc(cc1)O)C(C)C

InChI=1S/C19H27N3O5/c1-11(2)16(20)17(24)21-14(10-12-5-7-13(23)8-6-12)18(25)22-9-3-4-15(22)19(26)27/h5-8,11,14-16,23H,3-4,9-10,20H2,1-2H3,(H,21,24)(H,26,27)/t14-,15-,16-/m0/s1

InChIKey: PMKQKNBISAOSRI-JYJNAYRXSA-N


Peptide found in milk protein hydrolysates.

Abubakar A., Saito T., Kitazawa H., Kawai Y., Itoh T., 1998, Structural analysis of new antihypertensive peptides derived from cheese whey protein by proteinase K digestion. J. Dairy Sci., 81, 3131-3138

Peptide found in amaranth protein hydrolysate.

Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001) according to AHTPDB database; BIOPEP database of bioactive peptides; EROP-Moscow database
Neuropeptide according to ChEMBL database; EROP-Moscow database


Database reference:
AHTPDB: ID 1203; 1589; 1726; 2260; 2581; 3399; 3759; 4126; 4157; 4596; 4852; 4968; 5268; 5510; 5634; 5908; 5949; 6424; 6866

BIOPEP database of bioactive peptides: ID 3505

ChEMBL: ID CHEMBL389820

ChemSpider: ID 10077308

EROP-Moscow: ID E09270

PubChem: ID 11902985

ZINC: ID ZINC04899808